<p class="speakable">The <a href="https://www.foxnews.com/category/us/portland" rel="noopener" target="_blank">City of Portland</a> in Oregon said people were wounded Thursday afternoon in a shooting involving federal agents.</p><p class="speakable">Portland Police Bureau (PPB) <a href="https://www.foxnews.com/category/us/crime/police-and-law-enforcement" rel="noopener" target="_blank">officers</a> responded to reports of a shooting on the 10200 block of Southeast Main Street at about 2:18 p.m. local time and confirmed federal agents were involved, according to the city.</p><p>Fewer than 10 minutes later, at 2:24 p.m., officers were told a man who had been shot was calling and requesting help in the area of Northeast 146th Avenue and East Burnside. </p><p>Police responded and found a man and woman with apparent gunshot wounds, according to the city.</p><p><a href="https://www.foxnews.com/politics/noem-condemns-alleged-attack-ice-agents-stuck-snow-minneapolis-act-domestic-terrorism" rel="noopener" target="_blank"><strong>NOEM CONDEMNS ALLEGED ATTACK ON ICE AGENTS STUCK IN SNOW IN MINNEAPOLIS AS 'ACT OF DOMESTIC TERRORISM'</strong></a></p><p>They were taken to the hospital and their conditions are unknown.</p><p>Both scenes were secured by the PPB pending an investigation, officials said.</p><p>Sources told Fox News the federal agents involved were with U.S. Customs and Border Protection (<a href="https://www.foxnews.com/category/us/immigration/border-security" rel="noopener" target="_blank">CBP</a>).</p><p>No arrests have been confirmed.</p><p>"We are still in the early stages of this incident," PPB Chief Bob Day wrote in a statement. "We understand the heightened emotion and tension many are feeling in the wake of <a href="https://www.foxnews.com/category/us/us-regions/midwest/minnesota" rel="noopener" target="_blank">the shooting in Minneapolis</a>, but I am asking the community to remain calm as we work to learn more."</p><p><a href="https://www.foxnews.com/us/minneapolis-ice-shooting-protesters-set-up-camp-barricade-roads-schools-businesses-close-city-edge" rel="noopener" target="_blank"><strong>MINNEAPOLIS ICE SHOOTING PROTESTERS SET UP CAMP, BARRICADE ROADS AS SCHOOLS, BUSINESSES CLOSE IN CITY ON EDGE</strong></a></p><p>PPB officers were not involved in the incident, and "do not engage in immigration enforcement," according to city officials.</p><p>FBI agents were photographed at the scene.</p><p><a href="https://www.foxnews.com/category/us/democratic-party" rel="noopener" target="_blank">Sen. Ron Wyden</a>, D-Ore., reacted to the shooting on X, blaming the Trump administration for "inflaming violence."</p><p><a href="https://foxnews.onelink.me/xLDS?pid=AppArticleLink&amp;af_dp=foxnewsaf%3A%2F%2F&amp;af_web_dp=https%3A%2F%2Fwww.foxnews.com%2Fapps-products" rel="noopener" target="_blank"><strong>CLICK HERE TO DOWNLOAD THE FOX NEWS APP</strong></a></p><p>"I'm monitoring the first awful reports of two people shot in Portland by federal law enforcement," Wyden wrote in the post. "I'll keep you updated, but Trump's deployment of federal agents in my hometown is clearly inflaming violence--and must end."</p><p><i>This is a developing story. Please check back for updates.</i></p>