<p class="speakable">At least two people died Sunday <a href="https://www.foxnews.com/category/us/us-regions/southeast/virginia" rel="noopener" target="_blank">in Virginia</a> when a highway "road rage incident" reportedly spiraled into a violent <a href="https://www.foxnews.com/category/us/crime/mass-murder" rel="noopener" target="_blank">mass stabbing</a>, authorities said.</p><p class="speakable">The attack occurred on I-495 southbound near Little River Turnpike in Annandale, Fairfax County, roughly 30 minutes from Washington, D.C.</p><p>One of four stabbing victims, as well as a dog, died from the incident, authorities said. The suspect was also killed when <a href="https://www.foxnews.com/category/us/crime/police-and-law-enforcement" rel="noopener" target="_blank">responding officers</a> returned fire.</p><p>Officials said the attack does not appear to be terrorism-related.</p><p>"A Virginia State Police trooper was called to the scene at approximately 1:17 p.m. for a reported road rage incident," Virginia state police said. </p><p>"The stabbings occurred before or as the trooper was responding," authorities added in a statement to Fox News Digital.</p><p>Responding police reportedly found a male suspect armed with a knife. During the confrontation, the trooper reportedly shot the suspect in self-defense. Authorities added that the responding trooper was left unharmed.</p><p>State police identified the deceased victim as a 39-year-old woman who succumbed to her injuries. The dog involved was also fatally stabbed.</p><p><a href="https://www.foxnews.com/us/virginia-murder-suspect-bus-stop-stabbing-had-lengthy-criminal-history-multiple-dropped-charges" rel="noopener" target="_blank"><strong>VIRGINIA MURDER SUSPECT IN BUS STOP STABBING HAD LENGTHY CRIMINAL HISTORY, MULTIPLE DROPPED CHARGES</strong></a></p><p>The incident prompted a shutdown of the highway amid reports of a heavy police presence.</p><p>"I-495 and 495 Express Lanes southbound past Gallows Road is closed due to a major incident," the Virginia Department of Transportation’s Northern Virginia office said, adding that the lanes were "blocked due to police activity."</p><p><a href="https://foxnews.onelink.me/xLDS?pid=AppArticleLink&amp;af_dp=foxnewsaf%3A%2F%2F&amp;af_web_dp=https%3A%2F%2Fwww.foxnews.com%2Fapps-products" rel="noopener" target="_blank"><strong>CLICK HERE TO DOWNLOAD THE FOX NEWS APP</strong></a></p><p>The crash is under investigation.</p><p>The Fairfax County Police Department told Fox News Digital that it is assisting state police troopers.</p>