<p class="speakable">Emergency crews are treating dozens of patients after a tour bus crashed and rolled over on the highway Friday afternoon in <a href="https://www.foxnews.com/category/us/us-regions/northeast/new-york" rel="noopener" target="_blank">Genesee County, New York.</a></p><p class="speakable">The Town of Pembroke told Fox News Digital firefighters reported up to 52 patients at mile marker 4039.</p><p>Officials said some passengers were ejected from the vehicle and <a href="https://www.foxnews.com/category/disasters" rel="noopener" target="_blank">others were trapped.</a></p><p><a href="https://www.foxnews.com/us/heart-stopping-video-shows-helicopter-flip-crash-near-michigan-waterfront-restaurant" rel="noopener" target="_blank"><strong><u>HEART-STOPPING VIDEO SHOWS HELICOPTER FLIP AND CRASH NEAR MICHIGAN WATERFRONT RESTAURANT</u></strong></a></p><p>At least four <a href="https://www.foxnews.com/health" rel="noopener" target="_blank">Mercy Flight helicopters</a> have been called to the scene, according to town officials.</p><p>It is unclear if there were any fatalities.</p><p>New York Gov. <a href="https://foxnews.com/person/h/kathy-hochul" rel="noopener" target="_blank">Kathy Hochul</a> said she had been briefed.</p><p>"My team is coordinating closely with [<a href="https://www.foxnews.com/category/us/crime/police-and-law-enforcement" rel="noopener" target="_blank">New York State Police</a>] and local officials who are working to rescue and provide assistance to everyone involved," Hochul wrote in an X post.</p><p><a href="https://www.foxnews.com/us/new-york-police-officer-good-samaritans-save-68-year-old-woman-from-vehicle-engulfed-flames" rel="noopener" target="_blank"><strong><u>NEW YORK POLICE OFFICER AND GOOD SAMARITANS SAVE 68-YEAR-OLD WOMAN FROM VEHICLE ENGULFED IN FLAMES</u></strong></a></p><p>The cause of the crash has not yet been released.</p><p>New York State Police confirmed all lanes are closed.</p><p><a href="https://www.foxnews.com/us/sport-fishing-boat-violently-crashes-meschutt-beach-jetty-injuring-people" rel="noopener" target="_blank"><strong><u>SPORT FISHING BOAT VIOLENTLY CRASHES INTO MESCHUTT BEACH JETTY, INJURING FOUR</u></strong></a></p><p>New York State Thruway Authority officials said to avoid the area.</p><p>Pembroke is a rural town in Genesee County, about 45 minutes from Buffalo.</p><p><a href="https://www.foxnews.com/apps-products" rel="noopener" target="_blank"><strong><u>CLICK HERE TO GET THE FOX NEWS APP</u></strong></a></p><p>The Genesee County Sheriff's Office declined inquiries from Fox News Digital. </p><p>New York State Police, the Genesee County manager and Genesee County Fire Department could not immediately be reached.</p><p><i>This is a developing story and will be updated.</i></p>